Blog & News
The latest scientific articles and news from the world of stem cell applications, genetics, and biotechnology.
PGT-A: Confirm Your Embryos' Chromosomal Integrity Before Transfer
PGT-A (Preimplantation Genetic Testing for Aneuploidy) evaluates the chromosomal integrity of your embryos before transfer, using next-generation sequencing to improve IVF success rates.
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mRNA Cancer Vaccines and Neoantigens: What Did the KEYNOTE-942 Trial Show in Melanoma?
The combination of mRNA-4157/V940 and Keytruda reduced the risk of recurrence in high-risk melanoma in the Phase 2b KEYNOTE-942 trial. Phase 3 process and current status.
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For Which Types of Cancer Is a Personalized Vaccine Approach Being Evaluated? Mutation Burden Guide
Tumor mutation burden is associated with immunotherapy response. The scientific rationale for a personalized vaccine approach in cancers such as melanoma, NSCLC, and glioblastoma.
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FDA-Approved Cancer Vaccine Sipuleucel-T: Dendritic Cell Therapy for Prostate Cancer
Sipuleucel-T (Provenge) is the first FDA-approved cellular cancer immunotherapy. Dendritic cell technology, the IMPACT study, and its use in prostate cancer.
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What Is a Personalized Cancer Vaccine? Tumor Lysate, Dendritic Cells, and the mRNA Approach
Personalized cancer vaccines combine tumor lysate, dendritic cell, and mRNA neoantigen technologies. Their scientific basis and current status of clinical trials.
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DCVax-L and Dendritic Cell Vaccine for Glioblastoma: Phase 3 Data and Approval Status
DCVax-L is a dendritic cell + tumor lysate vaccine being studied in patients with glioblastoma. Phase 3 results, survival data, and current FDA/MHRA approval status
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